ABSTRACT
<p><b>OBJECTIVE</b>To evaluate the value of colonoscopy in the diagnosis of colorectal cancer.</p><p><b>METHODS</b>The data of colonoscopy in 1751 patients from May 2003 to June 2006 were retrospectively analyzed.</p><p><b>RESULTS</b>Of these 1751 colonoscopies, 643 colorectal cancers (36.7%) were detected. The age of most patients was between 40 and 60 years, and hematochezia was the major syndrome for these patients. 351 patients (54.6%) had lump type, 211 (32.8%) ulcerous type, 81 (12.6%) ulcerous infiltration type. 511 colorectal cancers (79.5%) originated from the rectum or sigmoid colon. Simultaneous double primary carcinoma was found in 15 cases (2.3%). Multiple primary cancer was observed in 2 cases. Furthermore 254 colorectal cancers (39.5%) were found to have concurrent colorectal polyps.</p><p><b>CONCLUSION</b>Colonoscopy of total colon and rectum is very helpful in diagnosis of colorectal cancer, which can reduce the rate of misdiagnosis and improve the survival.</p>
Subject(s)
Female , Humans , Male , Middle Aged , Adenocarcinoma , Diagnosis , Pathology , Colon , Pathology , Colonic Polyps , Diagnosis , Pathology , Colonoscopy , Methods , Colorectal Neoplasms , Diagnosis , Pathology , Diagnostic Errors , Gastrointestinal Hemorrhage , Diagnosis , Neoplasms, Multiple Primary , Diagnosis , Rectum , Pathology , Retrospective StudiesABSTRACT
<p><b>OBJECTIVE</b>To observe the effect of transcutaneous electrical acupoint stimulation (TEAS) on nausea and vomiting (N&V) induced by patient controlled intravenous analgesia (PCIA) with Tramadol.</p><p><b>METHODS</b>Sixty patients who were ready to receive scheduled operation for tumor in the head-neck region and post-operation PCIA, aged 39-65 years, with the physique grades I-II of ASA, were randomized into two groups, A and B, 30 in each group. The pre-operation medication, induction of analgesia and continuous anesthesia used in the two groups were the same. TEAS on bilateral Hegu (LI4) and Neiguan (PC6) points was intermittently applied to the patients in group A starting from 30 min before analgesia induction to 24 h after operation, and the incidence and score of nausea and vomiting, antiemetic used, visual analogue scores (VAS), and PCIA pressing times in 4 time segments (0-4, 4-8, 8-12 and 12-24 h after the operation was finished) were determined. The same management was applied to patients in Group B, with sham TEAS for control.</p><p><b>RESULTS</b>The incidence and degree of N&V, as well as the number of patients who needed remedial antiemetic in Group A were less than those in Group B. The VAS score and PCIA pressing time were lower in Group A than those in Group B in the corresponding time segments respectively.</p><p><b>CONCLUSION</b>TEAS could prevent N&V induced by PCIA with Tramadol.</p>
Subject(s)
Adult , Aged , Female , Humans , Male , Middle Aged , Acupuncture Points , Analgesia, Patient-Controlled , Analgesics, Opioid , Nausea , Tramadol , Transcutaneous Electric Nerve Stimulation , VomitingABSTRACT
Background and purpose:Through detection of MG7-Ag expression in various types of gastric mucosa biopsy tissues as well as serum,we studied their correlation and its clinical application value in the role of prediction of gastric precancerosis and its clinical significance.Methods:Using 125 samples of gastric mucosa biopsy tissues and corresponding sera(12 samples of normal gastric mucosa,21 samples of superficial gastritis,24 samples of gastric mucosal erosion and ulcer,15 samples of atrophic gastritis,22 samples of dysplasia,31 samples of gastric cancer)MG7-Ag expression in tissues was detected by SP immunohistochemical two-step staining;enzyme-linked immunosorbent assay was used to detect serum content of antigen MG7.Results:No expression of MG7 was detected in 12 samples of normal gastric mucosa and the positive expression rate of MGT-Ag was 93.55% in 31 samples of gastric cancer.In the order of superficial gastritis,gastric mucosal erosion,ulcer,atrophic gastritis,dysplasia and gastric cancer,expression rate of MG7 was increased sequentially(P